Layla Iskandar was born in Beirut on August 23, 1984.

She has studied advertising and marketing at the Lebanese University and got a degree in acting and theater directing.

Her first step in the musical world was at the age of sixteen when she got the gold medal in the category of « Tarab » song in the program « Studio El Fan ».

In 2004, Layla participated in the program Star Academy in its first season in the Middle East. In the following year, she starred as a singer and actress in the theater piece « Insan » and participated in a duet entitled « Lebanon » with the Kuwaiti artist Nabeel Shuail. Layla was chosen by the United Nations to support the campaign for immunodeficiency virus.

In 2007, she released a video clip for the khaliji song « Assalifa wa ma fiha » which allowed her to gain the title of « best artist to sing Khaliji » that year in a referendum by Dubai television.

A year later, she released a video clip for the song « Qader ala boudy » in the Egyptian dialect and in 2010 she released a song with the Lebanese rap group « Melichia » entitled « Bhebbo » and another solo song entitled « Al hobb min taraf wahad ».

Lately, Layla released her new single « Al ghabi ». The song's lyrics are by Sultan Al Majali and the music is by Fayez Al Said. Layla's three video clips were all directed by Layal Rajha.